The “female infidelity” gene test detects genetic variants in the AVPR1a gene linked to social bonding and monogamy. The AVPR1a gene provides instructions to make vasopressin receptor 1a, which binds vasopressin and transmits this signal into cells. Vasopressin is a hormone that controls water retention and blood pressure. However, when released in the brain vasopressin can influence social behavior.

In women who inherit the “female infidelity” variant vasopressin signalling is disrupted. This may explain why women with this version of the gene are more likely to engage in extra-pair mating or cheating.

There is no evidence that the five variants included in this test impacts sexual behavior in men. Another APVR1a variant is linked to infidelity in men, which is detected in the Male Pair-Bonding Gene AVPR1A test.